. 2020 Nov 28;25(23):5609. doi: 10.3390/molecules25235609

Table 1.

Phenylpropanoid glycosides accumulation (mg/100 g DW ± SD) and their specific productivity* (mg/L/day) in studied callus, suspension and bioreactor V. officinalis in vitro cultures.

			Verbascoside				Isoverbascoside				Total Content
			Content			Specific Productivity	Content			Specific Productivity	Total Content
Vo-C	Weight of inoculum	0.3 g	7154.93	±	201.31 ^a	105.31	442.81	±	8.95 ^a	6.52	7597.74	±	210.26 ^a
		0.6 g	7176.14	±	288.90 ^a	105.39	528.17	±	20.08 ^b	7.76	7704.31	±	308.98 ^a
		0.9 g	7248.66	±	253.76 ^a	120.49	609.26	±	22.48 ^c	10.13	7857.92	±	276.24 ^a
Vo-S		1.5 g	6845.25	±	441.38 ^b	67.67	264.36	±	12.15 ^d	2.61	7109.61	±	453.53 ^b
		3.0 g	7059.37	±	34.62 ^b	74.36	387.19	±	1.92 ^e	4.08	7446.56	±	36.54 ^c
		4.5 g	6288.95	±	193.62 ^c	63.88	477.25	±	11.52 ^a	4.85	6766.21	±	205.14 ^d
Vo-BB			7685.00	±	500.39 ^d	104.39	306.40	±	25.20 ^f	4.16	7991.40	±	525.59 ^a
Vo-STB			9176.87	±	172.34 ^e	115.20	339.91	±	41.90 ^g	4.27	9516.79	±	214.24 ^e

$* specific productivity = \frac{(maximum concentration for each molecule in \frac{m g}{100 g} DW) \times cumulative biomass in {gL}^{-1}}{100 g DW \times number of days after which the maximum concentration of the certain molecule was reached}$ Values are expressed as the mean ± SD (n = 3). Vo-C—V. officinalis callus culture extract; Vo-S—V. officinalis suspension culture extract; Vo-BB—V. officinalis balloon bioreactor culture extract; Vo-STB—V. officinalis stirred-tank bioreactor culture extract. ^a–g Different letters within the same column indicate significant differences between mean values (P < 0.05).