Table 1.

List of tested fucoidans, VEGF reduction.

Species	Origin	Conc [µg/mL]	Fucose [mol%]	TPC [μgGAE/mg]	MW [KDa]	ARPE-19	RPE
Saccharina latissima	North Atlantic	1–100	83.8	9.7	1407	Reduced at 10–100 µg/mL	Reduced at 10 µg/mL
Fucus serratus	Baltic Sea	1–100	40.6	50.3	605	Reduced at 1–100 µg/mL	No reduction
Fucus vesiculosus	Baltic Sea	1–100	59.2	35.1	1340	Reduced at 1, 50, 100 µg/mL	No reduction
Fucus distichus subsp. evanescens	Baltic Sea	1–100	96.1	25.8	188	Reduced at 1–100 µg/mL	No reduction
Laminaria digitata	North Atlantic	1–100	67.1	9.4	460	Reduced at 1–100 µg/mL	No reduction
Laminaria hyperborea	North Atlantic	1–100	97	n.d.	1548	Reduced at 50 and 100 µg/mL	Reduced at 50 µg/mL
Laminaria hyperborea	North Atlantic	1–100	97	n.d.	299	Reduced at 10–100 µg/mL	Reduced at 50 and 100 µg/mL
Laminaria hyperborea	North Atlantic	1–100	97	n.d.	26.9	Reduced at 50 and 100 µg/mL	No reduction
Saccharina latissima	North Atlantic	1–100	64.7	n.d.	>800	Reduced at 1–100 µg/mL	n.d.
Laminaria digitata	Baltic Sea	1–100	3.9	n.d.	322	Reduced at 10–100 µg/mL	n.d.
Fucus vesiculosus	Sigma Aldrich	1–100	n.d.	n.d.	n.d.	Reduced at 50 and 100 µg/mL	Reduced at 1–100 µg/mL
Fucus distichus subsp. evanescens	Baltic Sea	1–250	61.9	14.4	88.60	Reduced at 100 and 250 µg/mL	n.d.

References: [76,79,86,87,90,91]. Abbreviations: Conc = concentration; GAE = gallic acid equivalent; MW = molecular weight; n.d. = not determined; TPC = total phenol content; UM = uveal melanoma.