Table 1.
Patient characteristics and opioid prescriptions.
| Characteristic | Cohort (N = 24,752) |
|---|---|
| Age in years, median (IQR) | 53 (47–58) |
| Year of metastatic diagnosis date, N (%) | |
| 2006 | 1505 (6.1%) |
| 2007 | 2014 (8.1%) |
| 2008 | 2222 (9.0%) |
| 2009 | 2521 (10.2%) |
| 2010 | 2601 (10.5%) |
| 2011 | 3102 (12.5%) |
| 2012 | 2621 (10.6%) |
| 2013 | 2626 (10.6%) |
| 2014 | 2673 (10.8%) |
| 2015 | 2867 (11.6%) |
| Region, N (%) | |
| Northeast | 3736 (15.1%) |
| North central | 5951 (24.0%) |
| South | 10,188 (41.2%) |
| West | 4712 (19.0%) |
| Unknown | 165 (0.7%) |
| Charlson comorbidity index, N (%) | |
| 0 | 19,750 (79.8%) |
| ≥ 1 | 5002 (20.2%) |
| Anxiety, N (%) | 2116 (8.5%) |
| Depression, N (%) | 2202 (8.9%) |
| Severe mental illness, N (%) | 351 (1.4%) |
| Substance use disorder, N (%) | 1011 (4.1%) |
| Opioid prescription within 1 year prior to metastatic diagnosis date, N (%) | 11,579 (46.8%) |
| Number of opioid prescriptions [among patients with use prior to diagnosis], N (%) | |
| 1 | 5616 (48.5%) |
| 2 | 2327 (20.1%) |
| 3 | 1086 (9.4%) |
| 4 | 594 (5.1%) |
| 5 | 352 (3.0%) |
| 6 | 295 (2.5%) |
| ≥ 7 | 1309 (11.3%) |
| Opioid prescription within 1 year after metastatic diagnosis date, N (%) | 20,146 (81.4%) |
| Number of opioid prescriptions [among patients with use after diagnosis], N (%) | |
| 1 | 4903 (24.0%) |
| 2 | 4127 (20.2%) |
| 3 | 2701 (13.2%) |
| 4 | 1833 (9.0%) |
| 5 | 1279 (6.3%) |
| 6 | 913 (4.5%) |
| ≥ 7 | 4660 (22.8%) |