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. 2020 Dec 10;10:21641. doi: 10.1038/s41598-020-77806-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of changes in serum vitamin D levels (ng/ml) and gut microbiota composition in responders and non-responders to vitamin D supplementation. (A) Serum vitamin D levels pre- and post- supplementation in responders and non-responders. (B) Relative abundance of different bacterial phyla pre and post supplementation in responder and non-responder groups. (C) The ratio of Bacteroidetes to Firmicutes in responders and non-responders, pre- and post- vitamin D supplementation. The figure were generated using (RStudio v 1.2 with R v 3.6)⁸⁷.