Table 1.
Biochemical parameters of non-alcoholic fatty liver disease (NAFLD) in experimental mouse groups 1.
| Feeding Protocol | Ad Libitum | TRF |
|---|---|---|
| Number of mice | 8 | 10 |
| Mean daily food intake (kcal/day) | 11.6 ± 0.4 | 10.9 ± 0.1 |
| Liver weight (g) | 1.36 ± 0.06 | 1.25 ± 0.03 |
| Liver triglycerides (mg/g) | 178.6 ± 11.7 | 177.0 ± 10.6 |
| Liver cholesterol esters (mg/g) | 11.06 ± 0.93 | 11.28 ± 0.95 |
| Liver free cholesterol (mg/g) | 2.90 ± 0.44 | 2.56 ± 0.28 |
| Plasma ALT (U/L) | 24.4 ± 2.1 | 28.4 ± 8.6 |
| Plasma AST (U/L) | 67.4 ± 2.7 | 93.6 ± 20.0 |
| Plasma albumin (g/L) | 32.5 ± 0.6 | 34.0 ± 0.5 |
1 Diet-induced obese male 129S6 mice were fed western diet either ad libitum or on a time-restricted feeding (TRF) protocol for 14 days. Food intake was measured daily during the feeding protocol intervention period, and mean food intake per day over the course of the intervention was calculated. All other parameters were measured post-mortem.