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Relationship between nucleus area and rate of loss (half-life) over the course of model. RGC densities binned by nucleus area were plotted over the natural history of the OHT and pONT models before fitting to exponential decay equation (A). In both (B) OHT and (C) pONT models, smaller RGCs typically have shorter half-lives than larger cells, suggesting preferential loss of smaller RGCs from the retina.
