APC	antigen-presenting cells
BMDC	bone marrow-derived cells
CDN	cyclic dinucleotide
cGAMP	cyclic GMP-AMP
cGAS	cGAMP synthase
CNS	central nervous system
DNP	DNA nanoparticle
EAE	experimental autoimmune encephalomyelitis
ER	endoplasmic reticulum
HD	healthy donors
HLA-G	human leukocyte antigen G
IDO	indoleamine 2,3 dioxygenase
IFN	interferon
IFNAR	IFN α/β receptor
MBMEC	mouse brain microvascular endothelial cells
MS	multiple sclerosis
PAMP	pathogen-associated molecular patterns
PBMC	peripheral blood mononuclear cells
RRMS	relapse-remitting MS
RT-qPCR	quantitative real-time polymerase chain reaction
STING	stimulator of interferon gene