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. 2020 Dec 10;10:21672. doi: 10.1038/s41598-020-77702-x

Table 2.

Odds ratio for decreased kidney function.

Variables Kidney function: eGFR (mL/min per 1.73 m2
Men Women
Adjusted ORb 95% CI Adjusted ORb 95% CI
Uric acid level (mg/dL)c
Q1 1.00 1.00
Q2 1.49 (0.92–2.39) 1.41 (1.12–1.77)
Q3 1.70 (1.10–2.64) 2.24 (1.82–2.76)
Q4 3.02 (1.96–4.67) 3.12 (2.52–3.86)
Hyperuricemia 5.49 (3.64–8.29) 5.79 (4.37–7.66)
BMId
Normal or underweight (< 23.0) 1.00 1.00
Overweight (23.0–24.9) 1.45 (1.05–2.00) 0.87 (0.73–1.04)
Obese (≥ 25.0) 1.61 (1.17–2.22) 0.74 (0.60–0.90)
Waist circumference
Normal 1.00 1.00
Abdominal obesity 0.80 (0.60–1.05) 0.90 (0.73–1.11)
Age
< 40 1.00 1.00
40–49 1.58 (1.15–2.18) 1.42 (1.17–1.72)
50–59 1.36 (0.93–1.98) 1.61 (1.31–1.98)
60–69 2.30 (1.55–3.43) 2.24 (1.75–2.88)
≥ 70 4.63 (3.11–6.90) 3.14 (2.37–4.17)
Household income
Low 1.00 1.00
Mid-low 0.94 (0.66–1.34) 0.91 (0.74–1.12)
Mid-high 0.92 (0.66–1.29) 0.93 (0.75–1.15)
High 0.77 (0.55–1.08) 1.09 (0.87–1.36)
Educational level
≤ Highschool 1.00 1.00
≥ College 1.37 (1.04–1.79) 1.05 (0.88–1.25)
Region
Metropolitan 1.00 1.00
Rural 1.04 (0.84–1.29) 0.80 (0.70–0.92)
Occupational categoriese
White 1.05 (0.77–1.44) 1.06 (0.87–1.28)
Pink 0.52 (0.33–0.81) 0.81 (0.66–0.99)
Blue 0.87 (0.66–1.14) 0.89 (0.73–1.09)
Unemployed 1.00 1.00
Diabetes
Yes 1.30 (0.98–1.74) 1.38 (1.08–1.77)
No 1.00 1.00
Hypertension
Yes 2.19 (1.70–2.82) 1.28 (1.04–1.56)
No 1.00 1.00
Dyslipidemia
Yes 0.92 (0.70–1.23) 0.96 (0.80–1.14)
No 1.00 1.00
Smoking status
Current smoker 1.03 (0.78–1.37) 1.37 (1.03–1.83)
Ex-smoker 0.93 (0.69–1.25) 0.92 (0.69–1.24)
Non-smoker 1.00 1.00
Drinking status
Frequently 0.91 (0.70–1.18) 0.99 (0.86–1.14)
Occasionally 0.67 (0.49–0.92) 0.83 (0.64–1.08)
Never 1.00 1.00
Physical activity
Active 1.00 1.00
Inactive 0.96 (0.77–1.18) 0.97 (0.84–1.10)
Year
2016 1.04 (0.85–1.28) 1.08 (0.94–1.25)
2017 1.00 1.00

ªModification of Diet in Renal Disease estimated glomerular filtration rate for Korean population (mL/min per 1.73 m2) = 107.904 × (Creatinine in mg/dL)−1.009 × (age)−0.02 × 0.667 [if female].

bOR adjusted for all sociodemographic, economic, health-related factors considered in the study.

Q1: < 4.80 mg/dL, < 3.70 mg/dL; Q2: 4.80–5.49 mg/dL, 3.70–4.19 mg/dL; Q3: 5.50–6.09 mg/dL, 4.20–4.79 mg/dL; Q4: 6.10–6.99 mg/dL, 4.80–5.99 mg/dL; Hyperuricemia: ≥ 7.00 mg/dL, ≥ 6.00 mg/dL, respectively.

dBMI body mass index; Obesity status defined by BMI based on 2018 Clinical Practice Guidelines for Overweight and Obesity in Korea.

eThree groups (white, pink, blue) based on the International Standard Classification Occupations codes. Unemployed group includes housewives.