Skip to main content
. 2020 Dec 3;25(23):5719. doi: 10.3390/molecules25235719
BBB Blood–brain barrier
EGCG (−)-epigallocatechin gallate
BDNF Brain-derived neurotrophic factor
p-CREB Phosphor-(cyclic-AMP response element-binding protein)
SSBs Single-strand breaks
DSBs Double-strand breaks
ROS Reactive oxygen species
CNS Central nervous system
SOD Superoxide dismutase
GPX Glutathione peroxidase
O2 Superoxide anions
OH Hydroxyl radicals
H2O2 Hydrogen peroxide
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
SMAD Small mother against decapentaplegic
IL-1 Interleukin-1
TNF-α Tumor necrosis factor α
TGF-β Transforming growth factor β
IFN-γ Interferon γ
DAMPs Damage-associated molecular patterns
PRRs Pattern recognition receptors
TLRs Toll-like receptors
HMGB1 High mobility group Box 1
HSPs Heat shock proteins
NADPH Nicotinamide adenine dinucleotide phosphate
MAPK Mitogen-activated protein kinases
NHEJ Non-homologous end joining
ATM A-T mutated
ATR ATM and Rad3-related
DNA-PK DNA-dependent protein kinase
DRG Dorsal root ganglion
CHOP C/EBP-homologous protein
JNK Jun-N-terminal kinases
P13K Phosphatidylinositol-3-kinase
AKT Serine-threonin protein kinase
GSK3β Glycogen synthase kinase 3 β
NRF-2 Nuclear factor erythroid-2 related factor-2
DHF 5, 7-dihydroxyflavone
EGCG/AA NPs Nanoparticles of EGCG/ascorbic acid
MDA Malondialdehyde
GSH Glutathione
CAT Catalase
HO-1 Heme oxygenase-1
XO Xanthine oxidase
LOX Lipoxygenase
AO Aldehyde oxidase
COX-2 Cyclooxygenase-2
AP-1 Activated protein-1