Table 1.
Baseline characteristics of control mice (CM), STZ-induced diabetic mice (DM), and losartan-treated diabetic mice (LDM).
| CM (n = 6) | DM (n = 7) | LDM (n = 7) | |
|---|---|---|---|
| Body weight (g) | 26.6 (26.0, 26.9) | 22.6 (21.3, 23.1) *** | 25.3 (23.3, 25.9) |
| Blood glucose (mmol/L) | 192.5 (181.0, 223.0) | 519.0 (512.5, 543.0) *** | 509.0 (469.0, 522.0) |
| HbA1c (%) | 4.2 (4.1, 4.2) | 8.6 (8.4, 9.2) *** | 7.2 (6.6, 8.2) |
| Urine volume (mL/day) | 0.9 (0.6, 1.3) | 19.6 (17.6, 26.4) *** | 6.4 (4.3, 9.6) † |
| UACR (mg/mmol) | 22.1 (20.3, 26.7) | 102.2 (99.1, 112.9) ** | 36.9 (35.2, 49.6) †† |
The results are presented as the median (25th, 75th percentiles). * p < 0.05, ** p < 0.01, and *** p < 0.001 for the difference between CM and DM. † p < 0.05, †† p < 0.01, and ††† p < 0.001 for the difference between DM and LDM. HbA1c, hemoglobin A1c; UACR, urinary albumin/creatinine ratio; STZ, streptozotocin.