| RAGE | Receptor for advanced glycation end product |
| HMGB1 | High Mobility Group Box 1 |
| MSH | Melanocyte stimulating hormone |
| MC1-R | Melanocortin 1 receptor |
| CDKN2A | Cyclin-dependent kinase inhibitor 2A |
| MAPK | Mitogen-activated protein kinase |
| NRAS | Neuroblastoma RAS viral oncogene homolog |
| BRAF | V-raf murine sarcoma viral oncogene homolog B1 |
| PI3K | Phosphatidylinositol-3 kinase |
| mTOR | Mammalian target of rapamycin |
| NF1 | Neurofibromatosis type1 |
| ARID2 | AT-rich interactive domain-containing protein 2 |
| TP53 | Tumor protein p53 |
| PPP6C | Serine/threonine-protein phosphatase 6 catalytic subunit |
| DDX3X | DEAD-box helicase 3 X-linked |
| PTEN | Phosphatase and tension homology |
| RAC1 | ras-related C3 botulinum toxin substrate 1 |
| FBXW7 | F-box/WD repeat-containing protein 7 |
| SNX31 | sorting nexin 31 |
| PREX2 | phosphatidylinositol-3,4,5- trisphosphate-dependent rac exchange factor 2 |
| TACC1 | transforming acidic coiled-coil-containing protein 1 |
| KIT | KIT tyrosine-protein kinase |
| IDH1 | isocitrate dehydrogenase1 |
| RB1 | retinoblastoma protein 1 |
| SF3B1 | splicing factor 3b subunit 1 |
| CTNNB1 | catenin (cadherin-associate protein) beta 1 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| CDK4 | cyclin-dependent kinase 4 |
| RASA2 | ras p21 protein activator 2 |
| WT1 | Wilms’ tumor suppressor gene 1 |
| EZH2 | enhancer of zeste homolog 2 |
| STK19 | serine/threonine-protein kinase 19 |
| SSM | superficial spreading melanoma |
| AJCC | American joint commission in cancer |
| OS | Overall survival |
| DSS | Disease-specific survival |
| LDH | Lactate dehydrogenase |
| PD1L1 | Programmed cell death receptor 1 ligand 1 |
| PD-1 | Programmed cell death receptor 1 |
| IL-2 | Interleukin 2 |
| IFN-α | Interferon alpha |
| FDA | Food and drug administration |
| CTLA-4 | Cytotoxic T lymphocyte antigen 4 |
| MHC | Major histocompatibility complex |
| TM | Transmembrane |
| V | Variable |
| C1 | Constant domain 1 |
| C2 | Constant domain 2 |
| DAMPS | Damage-associated molecular patterns |
| AGE | Advanced glycation end products |
| TRPM-1 | Transient receptor potential melastatin-1 |
| SSSRs | S100 soil sensor receptor |
| EMMPRIN | Extracellular matrix metalloproteinase inducer |
| ALCAM | Activated leukocyte cell adhesion molecule |
| TLR-4 | Toll-like receptor 4 |
| NPTNβ | Neuroplastin β |
| MCAM | Melanoma cells adhesion molecule |
| NF-κB | Nuclear factor kappa beta |
| ROS | Reactive oxygen species |
| TPL2 | Tumor progression locus 2 |
| ETV4 | ETS translocation variant 4 |
| MMP-25 | Matrix metalloproteinase 25 |
| VEGF | Vascular endothelial growth factor |
| FGF | Fibroblast growth factor |
| CMM | Cutaneous malignant melanoma |
| MCP-1 | Monocyte chemoattractant protein 1 |
| Dia-1 | Diaphanous-1 |
| cdc 42 | Cell division control protein 42 |
| TIRAP | Toll-like receptor 2/4 adaptors |
| MyD88 | Myeloid differentiation primary response 88 |
| ERK | Extracellular signal-related kinase |
| JNK | C-Jun N-terminal kinase |
| TXNIP | Thioredoxin interacting protein |
| NLRP3 | NLR family pyrin domain containing 3 |
| JAK | Janus kinase |
| STAT | Signal transducer and activator of transcription |
| CREB | Cyclin AMP response element-binding protein |
| RSK2 | Ribosomal S6 kinase 2 |
| VCAM-1 | Vascular cell adhesion molecule 1 |
| ICAM-1 | Intercellular adhesion molecule 1 |
| TNF-α | Tumor necrosis factor alpha |
| NO | Nitric oxide |
| Tregs | Regulatory T cells |