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. 2020 Nov 26;21(23):8989. doi: 10.3390/ijms21238989
RAGE Receptor for advanced glycation end product
HMGB1 High Mobility Group Box 1
MSH Melanocyte stimulating hormone
MC1-R Melanocortin 1 receptor
CDKN2A Cyclin-dependent kinase inhibitor 2A
MAPK Mitogen-activated protein kinase
NRAS Neuroblastoma RAS viral oncogene homolog
BRAF V-raf murine sarcoma viral oncogene homolog B1
PI3K Phosphatidylinositol-3 kinase
mTOR Mammalian target of rapamycin
NF1 Neurofibromatosis type1
ARID2 AT-rich interactive domain-containing protein 2
TP53 Tumor protein p53
PPP6C Serine/threonine-protein phosphatase 6 catalytic subunit
DDX3X DEAD-box helicase 3 X-linked
PTEN Phosphatase and tension homology
RAC1 ras-related C3 botulinum toxin substrate 1
FBXW7 F-box/WD repeat-containing protein 7
SNX31 sorting nexin 31
PREX2 phosphatidylinositol-3,4,5- trisphosphate-dependent rac exchange factor 2
TACC1 transforming acidic coiled-coil-containing protein 1
KIT KIT tyrosine-protein kinase
IDH1 isocitrate dehydrogenase1
RB1 retinoblastoma protein 1
SF3B1 splicing factor 3b subunit 1
CTNNB1 catenin (cadherin-associate protein) beta 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
CDK4 cyclin-dependent kinase 4
RASA2 ras p21 protein activator 2
WT1 Wilms’ tumor suppressor gene 1
EZH2 enhancer of zeste homolog 2
STK19 serine/threonine-protein kinase 19
SSM superficial spreading melanoma
AJCC American joint commission in cancer
OS Overall survival
DSS Disease-specific survival
LDH Lactate dehydrogenase
PD1L1 Programmed cell death receptor 1 ligand 1
PD-1 Programmed cell death receptor 1
IL-2 Interleukin 2
IFN-α Interferon alpha
FDA Food and drug administration
CTLA-4 Cytotoxic T lymphocyte antigen 4
MHC Major histocompatibility complex
TM Transmembrane
V Variable
C1 Constant domain 1
C2 Constant domain 2
DAMPS Damage-associated molecular patterns
AGE Advanced glycation end products
TRPM-1 Transient receptor potential melastatin-1
SSSRs S100 soil sensor receptor
EMMPRIN Extracellular matrix metalloproteinase inducer
ALCAM Activated leukocyte cell adhesion molecule
TLR-4 Toll-like receptor 4
NPTNβ Neuroplastin β
MCAM Melanoma cells adhesion molecule
NF-κB Nuclear factor kappa beta
ROS Reactive oxygen species
TPL2 Tumor progression locus 2
ETV4 ETS translocation variant 4
MMP-25 Matrix metalloproteinase 25
VEGF Vascular endothelial growth factor
FGF Fibroblast growth factor
CMM Cutaneous malignant melanoma
MCP-1 Monocyte chemoattractant protein 1
Dia-1 Diaphanous-1
cdc 42 Cell division control protein 42
TIRAP Toll-like receptor 2/4 adaptors
MyD88 Myeloid differentiation primary response 88
ERK Extracellular signal-related kinase
JNK C-Jun N-terminal kinase
TXNIP Thioredoxin interacting protein
NLRP3 NLR family pyrin domain containing 3
JAK Janus kinase
STAT Signal transducer and activator of transcription
CREB Cyclin AMP response element-binding protein
RSK2 Ribosomal S6 kinase 2
VCAM-1 Vascular cell adhesion molecule 1
ICAM-1 Intercellular adhesion molecule 1
TNF-α Tumor necrosis factor alpha
NO Nitric oxide
Tregs Regulatory T cells