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. 2020 Dec 1;21(23):9163. doi: 10.3390/ijms21239163

Figure 2.

Figure 2

CAR constructs of various scFvs capable of targeting CD19. (A) Schematic representation of anti-CD19 CAR construct. It is a second-generation CAR composed of anti-CD19 scFv, CD28 transmembrane region, CD28 co-stimulatory domain, and CD3ζ signaling domain. (B) VH and VL sequences of eight different anti-CD19 scFvs.