Table 1.
Characteristics of the CTC isolation methods.
| Assay Characteristics | The CTC-FIND Method | The RareCyte Method |
|---|---|---|
| CTC detection strategy | Physical property-based isolation (size and deformability) |
Selection-free |
| * Markers used in the assay | DAPI, CK, EpCAM, CD45, CD66b, CD34, CD11b, CD14 |
DAPI, CK, EpCAM, CD45, CD66b, CD34, CD11b, CD14 |
| Staining | On a filter | On a slide |
| Scanning/Size measurement | CyteFinder® | CyteFinder® |
* DAPI: 4′,6-diamidino-2-phenylindole (nucleus marker); CD: cluster of designation; CD45, CD66b, CD34, CD11b, CD14: markers of lymphocytes, granulocytes, hematopoietic stem and progenitor cells, and endothelial cells; CK: cytokeratin; EpCAM: epithelial cell adhesion molecule. CK and EpCAM are epithelial markers used as markers of CTCs.