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. 2020 Dec 3;25(23):5699. doi: 10.3390/molecules25235699

Table 4.

Scientific research focused on the use of drone brood in the treatment of various health problems.

Therapeutic Action Effects Biological Model References
Fertility problems and libido reinforcing agent Alleviates the effects of disorders associated with the menopause in women, increases the body’s immune resistance, increases mental immunity, alleviates symptoms such as: increased heart rate and breathing, feeling hot, excessive sweating Humans [30,43]
Improvement in reproductive properties, increase in the weight in the seminal gland by nearly 22%, increase in the rate of recovery of sexual function, improvement in sperm quality, i.e., ejaculation volume, survival and mobility Boars, rams [47,51]
Decrease in cholesterol and triglycerides levels Lowering the level of cholesterol and triglycerides after two months of use Rats [52]
Hepatoprotective activities and stimulates the immune system Lowering the level of alanine transaminase, alkaline phosphatase and bilirubin in the blood serum Rats [53]
DNA obtained from drone brood protects liver tissue against the hepatotoxic effects of acetylsalicylic acid, buserelin and carbon tetrachloride Rats [54]
Fetal shielding properties Protect the fetus against the harmful effects of acetylsalicylic acid Rats [55]
Healing effect in nervous and mental diseases Improves the mental state of patients with depressive neurosis, fatigue, anorexia, feelings of helplessness Humans [43]
Positive effect on the symptoms of neurastemia (fatigue, weariness, dizziness) Humans [56]
Improvement in memory, reduction of psychomotor lability, return of sphincter control Humans [43]
Improvement of neurovegetative and sexual functions in elderly people Humans [32]
Antiatherosclerotic effect The administration of lyophilized brood administered to rats for two months decreased the content of cholesterol by nearly 50%, triglycerides by 25% and ß-lipoproteins by over 30% in the blood serum compared to the control group. Rats [52]
Thyroid disorders The concentration of thyroxine and triiodothyronine increased by 40%, while the thyroid stimulating hormone decreased by 37% after 30 days of brood administration Dogs [57]
Antioxidant effect Lowers the content of unoxidized substances in blood serum of animals fed drone brood by about 25% compared to control animals Rats [58]
Malnutrition in children Consumption of several doses resulted in weight gain, improvement in general health and appetite, as well as tissue tension. Humans [43]
Anaemia Administration of freeze-dried drone brood to mutant mice with hereditary haemolytic anemia increased their survival rate. The mouse survival was increased from 2 weeks to 7 months in 50% of the animals Mutant mice [59]
Other disease Means of treating urinary tract diseases, diabetes, diarrhea, relieving chest pain, migraines, constipation and to prevent stretch marks on the skin of pregnant women. Humans [24,60,61]