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. 2020 Dec 11;6:192. doi: 10.1186/s40814-020-00725-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Relationships between in utero HIV exposure and attainment of GMCD neurodevelopmental milestones 1–3 months (a) and 3–5 months (b) of age. There was no detected difference in the proportion of infants who were HUU (n = 8) compared to HEU (n = 14) who attained GMCD milestones at 1–3 months of age ([p > 0.05], Fisher’s exact), and no comparisons between infants who were HUU vs. HEU were made for 3–5-month milestones met, given that only 1/10 infants who were HUU at follow-up was 3–5 months of age. All infants met milestones when comparing to the GMCD standardisation sample, except for infants who were HUU for 1–3-month receptive language, large movement and play activities milestones, and infants who were HEU for fine movement milestones at 3–5 months of age. Bar graphs are proportion (%) attaining all age-appropriate GMCD milestones. GMCD Guide for Monitoring Child Development; HUU HIV-unexposed, uninfected; HEU HIV-exposed, uninfected