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. 2020 Nov 26;21(23):8995. doi: 10.3390/ijms21238995

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Gene-specific increases in H3K4me3 immediately after memory retrieval. (A) ChIP analysis showed an increase in histone H3 lysine 4 trimethylation (H3K4me3) levels at the Npas4 promoter, but not TSS, region at 5 min after retrieval compared to the no react (NR) group (n = 12 per group). (B) There were no changes in H3K4me3 levels in c-fos promoter or coding region 5 or 15 min after retrieval (n = 12 per group). (C) No changes were observed in monoubiquitination of histone H2B (H2Bubi) at the Npas4 promoter following retrieval. * Denotes p < 0.05 from No React.