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. 2020 Nov 30;25(23):5649. doi: 10.3390/molecules25235649

Table 1.

pH-sensitive chemical bonds and release mechanisms in the acidic conditions.

pH-Sensitive Bonds Chemical Mechanisms Applications in Ref.
Imine graphic file with name molecules-25-05649-i001.jpg [34,35,36,37,38,39,40,41,42]
Hydrazone graphic file with name molecules-25-05649-i002.jpg [43,44,45,46,47,48,49,50,51]
Oxime graphic file with name molecules-25-05649-i003.jpg [52,53,54,55,56]
Amide graphic file with name molecules-25-05649-i004.jpg [57,58,59,60,61,62,63,64,65]
Acetals graphic file with name molecules-25-05649-i005.jpg [66,67,68,69,70]
Orthoester graphic file with name molecules-25-05649-i006.jpg [71,72]