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A schematic depicting the therapeutic potential of mild MNP/AMF hyperthermia against biofilm infections. The application of mild MNP/AMF hyperthermia can enhance the susceptibility of S. aureus biofilm to antibiotics by facilitating their uptake to biofilm bacteria. Additionally, when applied to macrophages at lower thermal doses, the treatment of MNP/AMF can promote a macrophage-mediated host response for the clearance of intracellular bacteria via MNP-dependent generation of ROS.
