Table 2.
Group | Ctrl | Docetaxel, 10, QW | Sunitinib, | AJ-HP-β-CD | AJ-HP-β-CD |
---|---|---|---|---|---|
80→40, QD | (1 mg/Kg, QW) | (2 mg/Kg, QW) | |||
Day22 | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 |
Day25 | 160.76 ± 15.35 | 133.20 ± 13.34 | 84.30 ± 21.76 ** | 126.70 ± 29.78 | 129.69 ± 24.15 |
Day29 | 226.117 ± 26.82 | 195.30 ± 22.50 | 92.96 ± 27.57 ** | 171.30 ± 30.29 ** | 144.59 ± 20.81 |
Day32 | 279.26 ± 16.41 | 226.60 ± 36.36 | 80.60 ± 24.80 *** | 177.90 ± 31.69 *** | 108.59 ± 25.76 ** |
Day36 | 363.38 ± 34.04 | 288.90 ± 64.19 * | 76.40 ± 30.65 *** | 192.31 ± 32.03 *** | 109.99 ± 25.49 *** |
Day39 | 464.99 ± 42.54 | 364.20 ± 80.19 | 86.19 ± 35.07 *** | 218.52 ± 41.42 *** | 116.39 ± 30.53 *** |
Day42 | 606.04 ± 80.43 | 435.60 ± 114.31 | 80.18 ± 26.90 *** | 226.30 ± 39.39 *** | 112.39 ± 38.61 *** |
* p < 0.05, ** p < 0.01, and *** p < 0.005 compared with the control group, statistical analysis was calculated using two-way ANOVA with Tukey’s post hoc test (n = 6)