Table 1.

Lateral diffusion characteristics of Gα subunits in HEK293 cells in the presence of Gβ₁γ₂ and/or dopamine D₂ receptor

	Dapp (µm2 s−1)	Mf (%)	N
Gαsa	0.130 ± 0.004	84.5 ± 1.5	49
Gαs Gβ1γ2b	0.246 ± 0.009	92.4 ± 0.8	143
Gαs D2R	0.232 ± 0.009	89.0 ± 1.0	88
Gαsβ1γ2 D2R	0.245 ± 0.009	90.6 ± 1.1	110
Gαi1	0.316 ± 0.012	91.8 ± 1.4	55
Gαi1 Gβ1γ2	0.237 ± 0.010	88.2 ± 1.6	53
Gαi1 D2R	0.356 ± 0.014	92.2 ± 1.4	45
Gαi1β1γ2 D2R	0.291 ± 0.012	91.0 ± 1.2	60
Gαi2	0.474 ± 0.015	95.2 ± 0.7	120
Gαi2 Gβ1γ2	0.526 ± 0.019	94.1 ± 1.3	50
Gαi2 D2R	0.467 ± 0.020	93.1 ± 1.4	58
Gαi2β1γ2 D2R	0.345 ± 0.013	90.9 ± 1.3	60
Gαi3a	0.338 ± 0.022	94.2 ± 1.7	34
Gαi3 Gβ1γ2b	0.424 ± 0.014	93.5 ± 0.9	66
Gαi3 D2R	0.358 ± 0.016	90.1 ± 1.5	60
Gαi3β1γ2 D2R	0.381 ± 0.014	91.0 ± 1.4	50

In the experiments where the co-expression took place, the diffusion of Gα subunits was measured. Values represent the mean ± S.E.M

D_app—apparent diffusion coefficient, M_f—mobile fraction

^aData from Ref. [40]

^bData from Ref. [34]