Table 1.
ECG recorded time intervals in WT and JDP2 mice. ECGs were recorded non-invasively on conscious mice 1 and 5 weeks after JDP2 overexpression for 30 min. Post-acquisition ECG analysis was based on a shape recognition technique. Heart rate variability was calculated from the RR-values as a ratio of standard deviation/mean. * p < 0.05 vs. WT from n = 6–11 animals.
| ECG Recordings | 1 Week | 5 Weeks | ||
|---|---|---|---|---|
| WT | JDP2 | WT | JDP2 | |
| P-wave duration | 10.0 ± 0.9 ms | 10.6 ± 0.8 ms | 10.0 ± 1.5 ms | 11.6 ± 1.1 ms * |
| PQ-interval | 32.0 ± 5.1 ms | 32.3 ± 2.6 ms | 30.3 ± 7.0 ms | 35.1 ± 3.6 ms |
| QRS-complex | 14.3 ± 1.2 ms | 13.0 ± 1.2 ms | 13.9 ± 1.7 ms | 15.8 ± 2.3 ms * |
| RR-interval | 86.8 ± 5.0 ms | 84.9 ± 4.0 ms | 83.3 ± 4.1 ms | 84.5 ± 3.1 ms |
| HR-variability | 0.031 ± 0.013 | 0.042 ± 0.034 | 0.021 ± 0.01 | 0.027 ± 0.01 |
| QT-interval | 29.1 ± 0.7 ms | 29.1 ± 1.4 ms | 29.5 ± 1.8 ms | 31.3 ± 1.9 ms |
| n | 6 | 7 | 10 | 11 |