Scheme 2.
Synthesis of compounds 10–20. Reagents and conditions: (a) DMF, K2CO3, 2-chloro-N,N-dimethylethylamine hydrochloride, rt, or formaldehyde, morpholine, ethanol, reflux; (b) MeOH, 4-isopropylphenylhydrazine, rt; (c) BBr3, CH2Cl2, −70 °C.
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