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. 2020 Dec 7;25(23):5773. doi: 10.3390/molecules25235773

Table 3.

Inhibition data of new indole-3-carbaldehyde hydrazones 28–36 and 45.

graphic file with name molecules-25-05773-i018.jpg

Comp. R R1 Aβ40 Aggregation Inhibition
% at 100 μM IC50 (μM)
28 H graphic file with name molecules-25-05773-i019.jpg 18 ± 2
29 5-OCH3 graphic file with name molecules-25-05773-i020.jpg 56 ± 1
30 H graphic file with name molecules-25-05773-i021.jpg 13 ± 2
31 5-OCH3 9.2 ± 0.7
32 H graphic file with name molecules-25-05773-i022.jpg 8.4 ± 0.6
33 5-OCH3 22 ± 2
34 5-OCH3 graphic file with name molecules-25-05773-i023.jpg 20 ± 2
35 5-OCH3 graphic file with name molecules-25-05773-i024.jpg 12 ± 2
36 5-OCH3 graphic file with name molecules-25-05773-i025.jpg 13 ± 1
45 5-OCH3 graphic file with name molecules-25-05773-i026.jpg 0