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. 2020 Dec 4;25(23):5725. doi: 10.3390/molecules25235725

Table 1.

Demographic, clinical, and hematological features of COVID-19 survivors and non-survivors.

Global Cohort
(n = 119)
Survivors
(n = 90)
Non-Survivors
(n = 29)
p-Value
Age (Years) 72 (60–81) 68 (57–78) 80 (74–85) <0.001
Gender (F/M) 42/77 34/56 8/21 0.32
Smoking Status (No/Yes/Former) 67/36/16 51/27/12 16/9/4 0.99
BMI (Non-Obese/Obese) 92/27 68/22 24/5 0.42
P/F Ratio 278 ± 90 301 ± 79 208 ± 88 <0.001
Chest CT Severity Score 11.0 (6.0–21.0) 10.0 (6.0–19.5) 15.0 (10.5–21.5) 0.12
Intensity of Care (No, OT, RSni, RSi) 25/50/22/22 24/37/13/16 1/13/9/6 0.03
Interval between Disease Onset and Admission (Days) 6.5 (3.0–8.0) 7.0 (4.0–9.0) 4.0 (1.5–6.0) 0.006
Hospital Stay (Days) 15 (10–26) 20 (13–34) 6 (4–12) <0.001
Charlson Comorbidity Index 4.0 (2.0–7.0) 3.5 (2.0–6.0) 6.0 (5.0–8.0) <0.001
Cardiovascular Disease (No/Yes) 50/69 44/46 6/23 0.008
Respiratory Disease (No/Yes) 93/26 72/18 21/8 0.39
Kidney Disease (No/Yes) 102/17 77/13 25/4 0.93
Diabetes (No/Yes) 94/25 72/18 22/7 0.64
Cancer (No/Yes) 101/18 76/14 25/4 0.82
Autoimmunity (No/Yes) 113/6 85/5 28/1 0.65
ACE inhibitors (No/Yes) 96/23 75/15 21/8 0.20
ARBs (No/Yes) 96/23 73/17 23/6 0.83
WBC (×109 L) 6.74 (5.00–9.32) 6.47 (5.00–8.66) 9.16 (5.65–13.52) 0.006
Monocytes (×109 L) 0.35 (0.20–0.50) 0.40 (0.20–0.50) 0.30 (0.26–0.53) 0.85
Lymphocytes (×109 L) 0.90 (0.67–1.14) 1.00 (0.70–1.20) 0.70 (0.60–1.03) 0.012
Neutrophils (×109 L) 5.24 (6.30–7.58) 5.00 (3.56–6.30) 7.30 (3.75–11.15) 0.012
Platelets (×109 L) 204 (162–265) 211 (166–265) 184 (159–259) 0.43
RDW (%) 15.1 (14.1–16.3) 14.9 (13.7–16.4) 15.5 (14.8–16.1) 0.41
MPV (fL) 8.45 (8.10–9.00) 8.40 (8.08–8.92) 8.60 (8.18–9.320.37) 0.37

ACE: angiotensin converting enzyme; ARBs: angiotensin II receptor blockers; BMI: body mass index; COVID-19: coronavirus disease 2019; F: female; M: male; MPV, mean platelet volume; OT: oxygen therapy; RDW, red blood cell distribution width; RSi: invasive respiratory support; RSni: non-invasive respiratory support; WBC: white blood cells. All continuous variables are reported as medians and interquartile ranges. Statistical significance set at 0.05. All statistically significant values are reported in bold.