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. 2020 Dec 4;25(23):5725. doi: 10.3390/molecules25235725

Table 3.

Receiver operating characteristics (ROC) curves and prognostic accuracy of blood cell count-derived inflammation indexes.

AUC 95% CI p-Value Cut-off Sensitivity (%) Specificity (%)
AISI 0.640 0.546 to 0.726 0.034 >798 59 72
dNLR 0.664 0.571 to 0.748 0.014 >6.2 52 85
MLR 0.617 0.523 to 0.705 0.054 >0.364 69 57
MPR 0.558 0.464 to 0.649 0.37 >0.040 66 52
NLPR 0.706 0.615 to 0.787 0.0005 >0.019 66 75
NLR 0.697 0.605 to 0.778 0.002 >15.2 38 97
PLR 0.572 0.478 to 0.663 0.26 >240 59 58
SII 0.628 0.534 to 0.715 0.06 >1835 55 75
SIRI 0.659 0.567 to 0.744 0.013 >2.93 59 74

AISI, aggregate index of systemic inflammation (neutrophil*platelet* monocyte to lymphocyte ratio); AUC: area under the curve; CI: confidence interval; COVID-19: coronavirus disease 2019; dNLR, derived neutrophil to lymphocyte ratio; MLR, monocyte to lymphocyte ratio; MPR, mean platelet volume to platelet ratio; NLR, neutrophil to lymphocyte ratio; NLPR, neutrophil to lymphocyte*platelet ratio; PLR, platelet to lymphocyte ratio; SII, systemic immune-inflammation index (neutrophil*platelet to lymphocyte ratio); SIRI, systemic inflammation response index (neutrophil* monocyte to lymphocyte ratio). Statistical significance set at 0.05.