Figure 3.

Effects of carvone enantiomers on leukocyte infiltration in the lung of allergic mice following OVA-induced allergic airway inflammation. Twenty-four hours after the last challenge, lungs were fixed in 10% formalin, embedded in paraffin and sectioned. The tissue section slides were stained with HE. OVA-sensitized mice were treated with R-carvone (10 mg/Kg), S-carvone (10 mg/Kg) or dexamethasone (1 mg/Kg) or saline (vehicle) 1 h prior to each challenge. These analyses were performed by a blind observer using a light microscope with 400× magnifications. Each photomicrograph is representative of two independent experiments performed with five animals per group.