Table 1. Radiological findings and neurocognitive impairments in HIV-1-infected hemophiliacs.
| Items | Neurocognitive impairments | p | |
|---|---|---|---|
| + | - | ||
| MRI findings | |||
| + | 7 | 2 | p < 0.05 |
| - | 20 | 29 | |
| FDG-PET abnormalities | |||
| + | 15 | 22 | n.s. |
| - | 12 | 9 | |
A total of 58 HIV-1-infected hemophiliacs underwent the neuropsychological (NP) test battery, brain MRI, and FDG-PET. The correlations between radiological findings and neurocognitive impairments were examined by the χ2 analysis. Neurocognitive impairments were examined by the 14 NP tests that assessed 8 cognitive domains used in the J-HAND study (58). Positive MRI findings: scars of faint intracranial bleeding. MRI, magnetic resonance imaging; FDG-PET, 18F-fluorodeoxyglucose-positron emission tomography; n.s., not significant.