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. 2020 Dec 7;21(23):9333. doi: 10.3390/ijms21239333

Table 1.

Animals used in pharmacological-immunohistochemical experiments and blood sampling for interleukin-6 (IL-6) ELISA measurement. The differences in surviving animal numbers reflected the increased mortality of the SZR104 + PILO-treated animals (see Results).

Pharmacological Treatment Number of Surviving Animals Experimental Procedures
Control animals: 0.9% NaCl i.p. injection 12 Blood samples (8 animals).
Immunohistochemistry (4 animals).
Pilocarpine-treated: 190 mg/kg PILO, i.p. injection 21 Blood samples (18 animals).
Immunohistochemistry (4 animals).
SZR104 solution i.p. (358 mg/kg) 12 Blood samples (8 animals).
Immunohistochemistry (4 animals).
SZR104 (358 mg/kg) and PILO (190 mg/kg) i.p. injections 8 Blood samples (4 animals).
Immunohistochemistry (4 animals).