Table 6. Surgical indication, long-term outcomes, and prognostic factors reported in the previous and present studies.
| Author | Year | n | Surgical indication | Median OS (month) |
5-year RFS rate (%) |
5-year OS rate (%) |
Prognostic factors for poor survival |
|---|---|---|---|---|---|---|---|
| Shildberg et al. | 2012 | 31 | Without other distal metastasis | NS | NS | 13 | Multiple liver metastases R1/R2 resection Synchronous |
| Takemura et al. | 2012 | 64 | Three or fewer GELMs (More liver metastases at the surgeon's discretion) Only R0 resection |
34 | 27 | 37 | ≥ 5 cm in size pT4 of primary tumor |
| Wang et al. | 2012 | 30 | Without other distal metastasis preoperatively Synchronous GELMs Only R0 resection |
11 | NS | 16.7 | Peritoneal dissemination Multiple distal metastases |
| Kinoshita et al. | 2014 | 256† | Three or fewer GELMs (More liver metastases at the surgeon's discretion) Only R0 resection |
31 | 30.1 | 31.1 | pT4 of primary tumor ≥ 5 cm in size ≥ 3 GELMs |
| Tiberio et al. | 2014 | 53† | Without other distal metastasis | 34 | NS | 31.5 | ≥ 6 cm in size D2 dissection |
| Wang et al. | 2014 | 39 | Without other distal metastasis | 14 | 7.7 | 10.3 | Lymph node metastasis Multiple distal metastases |
| Guner et al. | 2015 | 68† | Not stated in detail (case by case) | 24 | 26.0 | 30.0 | ≥ 3 cm in size |
| Liu et al. | 2015 | 35 | Without other distal metastasis | 33 | NS | 14.3 | Lymphovascular invasion Multiple liver metastasis |
| Oki et al. | 2015 | 94† | Without other distal metastasis | 34 | 27.7 | 42.3 | ≥ 3 cm in size Multiple GELMs ≥ N2 of primary tumor |
| Present study | 2018 | 31 | Three or fewer GELMs Controllable after chemotherapy Only R0 resection |
38 | 31.3 | 42.2 | Diffuse/other type R1/R2 resection |
Abbreviations: OS, overall survivals; RFS, recurrence-free survivals; GELM, gastric/esophagogastric-junction liver metastasis; NS, not stated. †, Multicenter cohort study.