Table 2.

Literature review of Hormographiella aspergillata infections in humans published since 1971

References	Country	Year	Infection site	EORTC/MSG classification	Underlying disease	Diagnosis Samples - Methods		Antifungal treatment	Surgery	Outcome
Speller and MacIver [2].	England	1971	Heart	Proven	Prosthetic Valve	Autopsy	Histology + culture	None	Yes	Died
Nenoff et al. [5]	Germany	1997	Lung	Proven	ALL	Autopsy	Histology + culture	AmB	No	Died
Verweij et al. [6]	Netherlands	1997	Lung	Proven	ALL	Autopsy	Histology + culture + RFLP	AmB ➔ ITZ	No	Died
Surmont et al. [7]	Belgium	2002	Lung	Proven	Lymphoma	Transthoracic puncture	DE + culture	AmB	No	Alive
Lagrou et al. [8]	Belgium	2005	Lung	Probable	AML	BAL	DE + culture	CSF	No	Died
Greer et al. [9]	USA	2008	Heart	Proven	Valve prosthesis	Resected valve	Histology + culture	lAmB	Yes	Alive
Abuali et al. [10]	USA	2009	Skin	Proven	AML	Skin biopsy	Culture	VRZ ➔ PSZ + CSF ➔ lAmB + CSF	No	Died
Conen et al. [11]	Switzerland	2011	Lung, eye, CNS, blood	Proven	AML	Autopsy	Histology + culture	VRZ ➔ PSZ ➔ CSF	No	Died
			Lung	Proven	AML	Lung biopsy	Histology + culture	VRZ ➔ PSZ ➔ lAmB ➔ VRZ	Yes	Died
			Lung	Proven	AML	Lung biopsy	Histology + culture	VRZ ➔ lAmB ➔ VRZ	Yes	Died
Suarez et al. [12]	France	2011	Lung	Proven	BAL	Lung biopsy	DE + culture	CSF ➔ VRZ ➔ lAmB	No	Alive
			Lung	Proven	X-ALD	Autopsy	Histology + culture + PF-PCR	CSF ➔ lAmB	No	Died
Pang et al. [13]	France	2012	Lung	Proven	ALL	Lung biopsy	Culture	CSF ➔ VRZ ➔ lAmB	No	Alive
Bojic et al. [14]	Austria	2013	Skin, lung	Proven	AML	Skin biopsy	Histology	CSF ➔ lAmB + VRZ	Yes	Died
Corzo-León et al. [15]	USA	2015	Lung	Probable	AML	BAL	Culture	VRZ ➔ lAmB	No	Died
Heiblig et al. [16]	France	2015	Sinus, orbit, CNS	Proven	AML	Sinus biopsy	DE + culture	CSF ➔ PSZ ➔ lAmB + VRZ	Yes	Died
Nanno et al. [17]	Japan	2016	Lung, CNS, small intestine	Proven	MDS	Lung biopsy	Histology + culture + βDG	ITZ ➔ lAmB + CSF ➔ VRZ + MCF ➔ VRZ + lAmB	No	Died
Koncan et al. [18]	Italy	2016	Lung	Proven	MPAL	Lung resection	Culture + PF-PCR + βDG	PSZ ➔ VRZ	Yes	Alive
Correa-Martinez et al. [19]	Germany	2017	Skin	Proven	Nephroblastoma	Skin biopsy	Histology + culture	PSZ	Yes	Alive
Godet et al. [20]	France	2017	Lung	Proven	AML	Lung biopsy	DE + PF-PCR	VRZ ➔ lAmB (IV + nebulized)	Yes	Alive
Jain et al. [21]	India	2019	Eye	Proven	Intraocular lens implantation	Corneal tissue	DE + culture + PF-PCR	Natamycin + ITZ ➔ VRZ	Yes	Alive (loss of the eye)
Chauhan et al. [22]	USA	2019	Lung, CNS	Proven	CML	Autopsy	Histology + culture + PF-PCR + βDG	MCF	No	Died
Our report HA1	France	2019	Lung	Probable	AML	BAL	DE + PF-PCR + βDG	lAmB	No	Died

Search for previously published cases using the terms “Hormographiella aspergillata” or “Coprinus cinereus infection” in MEDLINE database

*ALL Acute lymphoid leukemia, AML Acute myeloid leukemia, BAL Biphenotypic acute leukemia, X-ALD X-linked adrenoleukodystrophy, CML Chronic myeloid leukemia, MDS Myelodysplasia syndrome, MPAL Mixed phenotype acute leukemia, CNS Central nervous system, AmB Deoxycholate amphotericin B, ITZ Itraconazole, CSF Caspofungin, VRZ Voriconazole, PSZ Posaconazole, lAmB Liposomal amphotericin B, MCF Micafungin, IV Intravenous, RFLP Restriction fragment length polymorphism, DE Direct examination, PF-PCR Pan-fungal-polymerization chain reaction, βDG 1, 3-beta-D glucan