Table 2.
Number of birth defects in specific organ system from included studies
| Author(s) | Specific organ system | Circulatory system | Genitourinary system | Musculoskeletal system | Digestive system | Nervous system | Face | Beckwith-Weidemann syndrome | Poland syndrome |
|---|---|---|---|---|---|---|---|---|---|
| Deemeh [18] | AOA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| ICSI | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Miller [15] | AOAa | 4 | 2 | 2 | 0 | 0 | 0 | 1 | 0 |
| ICSIb | 8 | 5 | 3 | 2 | 3 | 1 | 0 | 0 | |
| Li B [17] | AOA | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| ICSI | 20 | 1 | 3 | 0 | 0 | 3 | 0 | 1 |
ICSI intracytoplasmic sperm injection, AOA artificial oocyte activation
aIn the AOA group, one case with several structural defects (dysplastic kidney, reflux, ventricular septal defect) and another case with ventricular septal defect, interrupted inferior vena cava and short thumb with low insertion of right hand
bIn the ICSI group, one case with both hypospadias and ventricular septal defect