Figure 5.
lncRNA MAPKAPK5-AS1 promotes thyroid cancer progression by targeting miR-519e-5p/YWHAH. A) RT-qPCR assay was implemented to certify transfection efficiency for miR-519e-5p inhibitor and MAPKAPK5-AS1 siRNAs. B-F) CCK-8, EdU, flow cytometry, wound healing, and transwell assays were employed to estimate the role of the MAPKAPK5-AS1/miR-519e-5p/YWHAH axis in BCPAP cell proliferation, migration, invasion and apoptosis; **p<0.01 vs sh-NC + NC inhibitor, ##p<0.01 vs sh-MAPKAPK5- AS1 + NC inhibitor, △p<0.01 vs sh-MAPKAPK5-AS1 + miR-519e-5p inhibitor.