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(A) Normal, (B) Untreated, (C) AF2240-i-treated and (D) rAF-IL12-treated. Normal hepatocytes with obvious central vein shown in the normal group and rAF-IL12-treated group. Note the liver metastasis (yellow arrow) and inflammatory infiltrates (green arrow) in the untreated and AF2240-i groups. S, blood sinusoids; CV, central vein. Magnification: 400X; H&E scale bar = 50 µm.
