Fig. 2.

Normal cortical interneurons in IN-PS cDKO mice at 2 months of age. a Nissl staining of comparable sagittal sections of IN-PS cDKO mice and littermate control brains at 2 months of age shows normal gross morphology in the neocortex (NCX) and hippocampus (HP) of IN-PS cDKO mice. b Stereological quantification shows similar volume of the NCX (p = 0.41, Student’s t-test) and HP (p = 0.55) between IN-PS cDKO and control mice. c GAD67 immunostaining of comparable sagittal sections in the neocortex and hippocampal area CA1 of IN-PS cDKO and littermate control brains at 2 months of age. d Stereological quantification shows similar numbers of GAD67-immunoreactive neurons in the NCX (p = 0.45, Student’s t-test) and HP (p = 0.23) between IN-PS cDKO and control mice. Scale bar: 100 μm. All data are presented as the mean ± SEM. The value in the column indicates the number of mice used in each experiment