Table 3.

Adverse events of sorafenib treatment

	All (n = 13)
Event	Any grade	Grade 1	Grade 2	Grade 3	Grade 4
Palmar‐plantar erythrodysesthesia	7 (53.8)	6 (46.1)	1 (7.7)	0 (0)	0 (0)
Fatigue	4 (30.7)	4 (30.7)	0 (0)	0 (0)	0 (0)
Decreased appetite	4 (30.7)	4 (30.7)	0 (0)	0 (0)	0 (0)
Hypertension	4 (30.7)	2 (15.4)	2 (15.4)	0 (0)	0 (0)
Diarrhea	4 (30.7)	2 (15.4)	2 (15.4)	0 (0)	0 (0)
Decreased platelet count	2 (15.4)	2 (15.4)	0 (0)	0 (0)	0 (0)
Dysphonia	2 (15.4)	2 (15.4)	0 (0)	0 (0)	0 (0)
Increased blood bilirubin	1 (7.7)	0 (0)	1 (7.7)	0 (0)	0 (0)
Elevated aspartate aminotransferase	1 (7.7)	1 (7.7)	0 (0)	0 (0)	0 (0)
Elevated alanine aminotransferase	1 (7.7)	1 (7.7)	0 (0)	0 (0)	0 (0)