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. Author manuscript; available in PMC: 2020 Dec 11.
Published in final edited form as: Curr Pharmacol Rep. 2019 Oct 19;5(6):481–490. doi: 10.1007/s40495-019-00200-w

Table 1.

General changes in RNA expression of P450s in adult liver of GF mice compared to CV mice.

Family and individual P450s RNA expression change in GF mice compared to CV mice Reference
Cyp1a and 2a Increased 51-143% [41]
Cyp2b Decreased 57% [41, 43]
Cyp2c Increased minimally or no change [40]
Cyp2e1 Increased about 100% or no change [40, 41]
Cyp3a Decreased up to 87% [40, 41, 43]
Cyp4a Increased up to 200% [40, 41]