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. Author manuscript; available in PMC: 2020 Dec 11.
Published in final edited form as: Curr Pharmacol Rep. 2019 Oct 19;5(6):481–490. doi: 10.1007/s40495-019-00200-w

Table 2.

General changes in RNA expression of transcription factors and nuclear receptors that regulate P450s in adult liver of GF mice compared to CV mice.

Transcription factors and nuclear receptors RNA expression change in GF mice compared to CV mice Reference
AHR Increased about 50% [40]
CAR Increased about 100% [40]
PXR Increased about 33% [40]
PPARα Increased about 100% [40]
Nrf2 Increased about 75% [40]