. 2020 Dec;9(4):145–153. doi: 10.22099/mbrc.2020.37181.1500

Table 2.

The selected 12 mRNA fold changes and the comparisons of LF vs. DMSO and PRP vs. SHAM groups at 3, 7, and 14 days

	LF *vs.* DMSO			DMSO *vs.* SHAM
	Day 3	Day 7	Day 14	Day 3	Day 7	Day 14
	FC (Mean±SD)	FC (Mean±SD)	FC (Mean±SD)	FC (Mean±SD)	FC (Mean±SD)	FC (Mean±SD)
	p	p	p	p	p	p
*Angpt1*	2.707±0.469	0.985±0.197	0.401±0.061	36.100 ±6.618	71.146 ±12.814	4.032±0.661
	0.036	0.871	0.008	*0.002*	*0.002*	0.431
*Col1a1*	5.573±0.891	0.719±0.135	0.063±0.011	7864.288 ±1496.398	1723.487±275.940	737.185±141.278
*Col1a1*	0.143	0.877	0.007	*0.002*	*0.002*	*0.002*
*Col3a1*	0.898±0.152	0.419±0.079	0.653±0.117	100.469 ±16.059	11.269±1.801	1.148±0.218
*Col3a1*	0.435	0.038	0.142	*0.002*	0.144	0.877
*Ctgf*	-16.391±3.277	-142.853 ±22.857	-62.016 ±11.007	5.968±1.004	1.597±0.256	0.050±0.009
*Ctgf*	0.007	*0.002*	*0.002*	0.002	0.876	0.005
*Cxcl11*	-568.181 ±108.527	-26775.092 ±5167.389	-1374.462 ±230.832	-19.609±3.009	-27.783±4.439	-704.225 ±135.213
*Cxcl11*	*0.002*	*0.001*	*0.001*	0.002	0.008	*0.002*
*Cxcl15*	-794.759 ±129.723	-10879.423±1951.628	-1725.927 ±323.362	-66.239±12.823	-120.106±20.872	-1994.457±342.562
*Cxcl15*	*0.001*	*0.001*	*0.001*	*0.002*	*0.002*	*0.002*
*Egfr*	-7727.877±1491.542	-10306.633 ±1850.298	-36238.319 ±6486.604	-138.435±23.976	-2047.465±421.838	-11048.203±2010.289
*Egfr*	*0.002*	*0.001*	*0.001*	*0.002*	*0.002*	*0.001*
*IL10*	-174.655 ±33.009	-1626.852 ±317.074	-1776.433 ±341.588	-1.967±0.393	-30.986±5.484	-2981.850±533.752
*IL10*	*0.002*	*0.001*	*0.001*	0.149	0.002	*0.001*
*Mmp1*	-6.774±1.327	-514.941±85.480	-119.158 ±20.894	8.060±1.141	5.518±0.855	0.030±0.006
*Mmp1*	0.009	*0.002*	*0.002*	0.030	0.144	0.037
*Mmp7*	-13.131±2.405	-1195.943 ±233.633	-322.913 ±62.43	2.864±0.514	2.302±0.412	0.023±0.004
*Mmp7*	0.006	*0.001*	*0.002*	0.147	0.147	*0.003*
*Tgfa*	-21.432±3.486	-2580.530 ±402.480	-2792.531 ±67.173	0.476±0.092	1.200±0.213	-363.160±61.502
*Tgfa*	0.005	*0.001*	*0.001*	0.436	0.870	*0.002*
*Tgfb1*	-80.795 ±14.358	-2088.964 ±396.511	-22.551±3.936	0.330±0.056	-75.570±1.277	-565.641±100.522
*Tgfb1*	*0.002*	*0.001*	0.002	0.022	*0.002*	*0.002*

Fold Change values ((FC)=2^-ΔΔCt) were obtained from triplicate measurement, p values were determined using the ΔCt of both groups. The statistically significance was accepted for fivefold FC (FC<(2^-5 =0.031), or FC>(2⁵=32)), and p<0.0042. Up- and down-regulated genes were indicated in bold, statistically significant p values were presented in bold italic.