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. 2020 Dec 11;15(12):e0243322. doi: 10.1371/journal.pone.0243322

Table 1. Compilation of trends underlying the non-demographic factors.

Epidemiology Declining incidence rates due to success in prevention, health care and rehabilitation followed by changes in the spectrum of diseases
Improved chances of survival in potentially life-threatening diseases through improved medical care
Structural changes in health care Introduction of new therapy options
Structural changes within the inpatient care sector, e.g. hospital closures, mergers, etc
Patient shifting between the health care sectors e.g. between inpatient and ambulatory or rehabilitative care
Introduction of new classification systems, e.g. DRG-system
Further legal changes to the billing of services
changes in the utilization, e.g. changes in the use of emergency care
Change of non-demographic structural characteristics of the population socio-structural changes of subsequent birth cohorts

Source: [17]