Table 3. Percent HDF viability (cell proliferation) of compounds from D. bulbifera and A. vera gel.
| Sample | % Viability of HDFs at various concentrations (mean ± S.E.M.) (μM) | |||||
|---|---|---|---|---|---|---|
| 0 | 1 | 3 | 10 | 30 | 100 | |
| 8-Epidiosbulbin E acetate (1) | 100.00 ± 1.99 | 132.02 ± 3.87* | 107.82 ± 4.71 | 108.96 ± 3.65 | 127.85 ± 4.31* | 122.47 ± 4.28* |
| 15,16-Epoxy-6α-O-acetyl-8β-hydroxy-19-nor-clero-13(16),14-diene-17,12;18,2-diolide (2) | 100.00 ± 1.99 | 118.64 ± 2.87* | 137.65 ± 4.51* | 111.99 ± 4.76 | 113.04 ± 3.93 | 107.49 ± 3.14 |
| Sitosterol-β-D-glucoside (3) | 100.00 ± 1.19 | 123.93 ± 6.23* | 97.76 ± 3.27 | 112.43 ± 2.96 | 103.90 ± 4.82 | 94.67 ± 4.01* |
| 3,5-Dimethoxyquercetin (4) | 100.00 ± 1.19 | 96.62 ± 1.34 | 104.13 ± 1.69 | 105.65 ± 2.59 | 110.98 ± 2.45* | 108.33 ± 0.59 |
| (+)-Catechin (5) | 100.00 ± 1.52 | 143.20 ± 3.04* | 151.90 ± 4.89* | 130.86 ± 3.00* | 137.47 ± 3.83* | 121.15 ± 2.98* |
| Quercetin (6) | 100.00 ± 1.41 | 98.03 ± 0.91 | 131.80 ± 2.76* | 131.95 ± 1.56* | 113.36 ± 2.49* | 117.96 ± 3.33* |
| Kaempferol (7) | 100.00 ± 2.44 | 92.71 ± 1.63 | 98.88 ± 2.43* | 94.98 ± 1.94* | 98.57 ± 1.13* | 121.02 ± 3.10* |
| Allantoin (8) | 100.00 ± 1.52 | 130.31 ± 1.85* | 108.57 ± 4.19 | 106.10 ± 2.54 | 105.27 ± 3.98 | 111.89 ± 2.74 |
| 2,4,3',5'-Tetrahydroxybibenzyl (9) | 100.00 ± 2.44 | 78.87 ± 3.98* | 110.70 ± 1.09 | 111.32 ± 1.16 | 99.61 ± 1.34 | 105.65 ± 3.79 |
| 2,4,6,7-Tetrahydroxy-9,10 dihydrophenanthrene (10) | 100.00 ± 2.08 | 109.01 ± 4.03* | 108.96 ± 1.56 | 98.00 ± 3.22* | 99.92 ± 3.83 | 111.82 ± 2.69 |
| Myricetin (11) | 100.00 ± 2.08 | 111.53 ± 1.05* | 115.92 ± 1.16* | 112.44 ± 4.33 | 110.34 ± 1.20 | 90.90 ± 1.47* |
| A. vera gel (μg/ml) | 100.00 ± 0.76 | 98.38 ± 1.63 | 105.88 ± 4.72 | 107.00 ± 2.67 | 104.76 ± 4.21 | 107.03 ± 4.12 |
*Statistically significant difference between A. vera gel and the sample, p < 0.05 (mean ± S.E.M. of three determinations).