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. 2020 Dec 11;15(12):e0243632. doi: 10.1371/journal.pone.0243632

Table 4. Effect of fractions from D. bulbifera bulbils on HDF migration.

Sample Dose (μg/ml) Length between the scratches (μm) Rate of cell migration (%)
Day 0 Day 1 Day 2 Day 3 Day 1 Day 2 Day 3
Control - 1428.42 ± 9.67 810.57 ± 7.31 423.25 ± 17.24 195.10 ± 8.65 43.25 ± 0.51a 70.37 ± 1.21 86.34 ± 0.61a
CHCl3 fraction 1 1317.69 ± 10.97 690.45 ± 6.85 278.29 ± 5.46 0.00 ± 0.00 47.60 ± 0.52*,a 78.88 ± 0.41*,a 100.00 ± 0.00*,a
3 1276.44 ± 2.09 618.37 ± 6.35 345.58 ± 4.58 0.00 ± 0.00 51.55 ± 0.50*,a 72.93 ± 0.36a 100.00 ± 0.00*,a
EtOAc fraction 1 1307.25 ± 1.38 670.08 ± 10.01 315.79 ± 5.06 0.00 ± 0.00 49.96 ± 0.75*,a 76.42 ± 0.38*,a 100.00 ± 0.00*,a
3 1339.11 ± 6.36 835.64 ± 16.41 400.41 ± 10.73 224.08 ± 9.76 37.60 ± 1.23* 70.10 ± 0.80 83.27 ± 0.73a
Water fraction 3 1358.95 ± 6.85 332.69 ± 28.03 0.00 ± 0.00 0.00 ± 0.00 75.52 ± 2.06*,a 100.00 ± 0.00*,a 100.00 ± 0.00*,a
10 1311.43 ± 13.33 675.30 ± 21.08 307.59 ± 8.03 0.00 ± 0.00 48.51 ± 1.61*,a 76.55 ± 0.61*,a 100.00 ± 0.00*,a
A. vera gel 1 1278.53 ± 8.29 872.72 ± 0.91 447.09 ± 10.02 82.38 ± 41.23 35.73 ± 0.07 67.08 ± 0.74 93.93 ± 3.04
3 1357.91 ± 24.70 825.19 ± 21.12 256.31 ± 0.65 136.23 ± 10.80 39.23 ± 1.56 81.12 ± 0.05 89.97 ± 0.80

*Statistically significant difference between the control and sample, p < 0.05 (mean ± S.E.M. of three determinations).

aStatistically significant difference between A. vera gel and the sample, p < 0.05 (mean ± S.E.M. of three determinations).