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. 2020 Dec 11;15(12):e0240339. doi: 10.1371/journal.pone.0240339

Table 4. Gene flow and genetic differentiation indices between the four HAV probable clusters estimated from VP3/VP1gene sequences.

Pop 1 Pop 2 Fst Nm Kxy Dxy Gst Da
Cluster-I Cluster-II 0.46 0.12 4.10 0.021 0.098 0.009
Cluster -I Cluster–III 0.52 0.12 4.75 0.024 0.108 0.013
Cluster-I Cluster-IV 0.52 0.12 4.61 0.023 0.073 0.011
Cluster-II Cluster-III 0.52 0.12 2.41 0.012 0.147 0.007
Cluster-II Cluster-IV 0.53 0.12 2.45 0.012 0.135 0.007
Cluster-III Cluster-IV 0.63 0.11 3.19 0.016 0.136 0.011

Fst: Wright’s F-statistics, pairwise genetic distance [22], Nm: Gene flow and population migration among populations [22, 23], Kxy: Average proportion of nucleotide differences between populations. Dxy: The average number of nucleotide substitutions per site between populations [20], Da: The number of net nucleotide substitutions per site between populations [20], Gst: Genetic differentiation index based on the frequency of haplotypes [24].