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. 2020 Dec 7;15:9875–9890. doi: 10.2147/IJN.S277845

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© 2020 Zhang et al.

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rrPPC/siSTAT3 complex suppressed C26 cells in vitro. (A) STAT3 mRNA levels in C26 cells after transfection (***P < 0.001); (B) STAT3 protein level of each treatment group; (C) anti-proliferation effect of rrPPC/siSTAT3 complex (***P < 0.001); (D) clonogenic assay used to detect the inhibitory effect of rrPPC/siSTAT3 complex; (E) average number of clones in each well (***P < 0.001; ****P < 0.0001); (F) inhibition rate calculated by clonogenic assay (****P < 0.0001); (G) rrPPC/siSTAT3 complex efficiently induced apoptosis in C26 cells (***P < 0.001).