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. 2020 Dec 11;40:47–54. doi: 10.1016/j.ajem.2020.12.006

Table 4.

Assessing clinical instability of COVID-19 patients

CDC Recognized Severe Symptoms of COVID-19 Concerning vital signs
Trouble breathing Intractable Fever (≥ 38 °C or 100.4 °F)
Cyanosis Respiratory rate ≥ 24 breaths/min
Inability to wake or stay awake (lethargy) Heart rate persistently over 100 beats/min
Persistent chest pain or pressure Systolic blood pressure persistently <90 mmHg
New confusion O2 saturation persistently <92% on room air