Table 1.

Patient data for brain samples.

Case	Group	Sex	Age at death	PMI (hours)	Clinical Diagnosis	Primary Path Diagnosis*	Other Path Diagnosis**
1	Ctrl	F	86	6.4	Control	N/A	AGD, limbic; VBI
2	Ctrl	F	81	30.3	MCI, amnestic	PART	None
3	Ctrl	M	76	8.2	Control	N/A	AGD, limbic
4	Ctrl	M	77	4.9	MCI, executive	AGD	VBI, microinfarct in cerebellar folia
5	Ctrl	F	86	7.8	Control	N/A	VBI, microinfarcts in claustrum and angular gyrus; AGD
6	GRN	M	66	10.1	DLB, ?bvFTD	LBD	Incipient FTLD‐TDP‐A
7	GRN	M	72	23.8	PPA‐mixed	FTLD‐TDP‐A	Subdural hematoma
8	GRN	M	74	30.9	nfvPPA, CBS	FTLD‐TDP‐A	None
9	GRN	F	73	20.7	nfvPPA, CBS	FTLD‐TDP‐A	None
10	GRN	F	66	7.4	bvFTD	FTLD‐TDP‐A	None
11	GRN	M	64	7.2	bvFTD	FTLD‐TDP‐A	None
12	GRN	F	70	9.1	PPA, unspecified	FTLD‐TDP‐A	Hippocampal Sclerosis, VBI, ischemic infarct
13	GRN	F	56	7.6	bvFTD	FTLD‐TDP‐A	None
14	GRN	F	78	19	mixed FTD	FTLD‐TDP‐A	None
15	GRN	F	66	17.1	bvFTD	FTLD‐TDP‐A	None
16	GRN	F	64	10.5	CBS	FTLD‐TDP‐A	None
17	GRN	M	72	7.2	AD	AD, FTLD‐TDP‐A?	Hippocampal Sclerosis
18	GRN	F	69	11	bvFTD	FTLD‐TDP‐A	Pre‐Hippocampal Sclerosis

AGD, argyrophilic grain disease; CAA, Cerebral amyloid angiopathy; CBS, Corticobasal syndrome; DLB, dementia with Lewy bodies; LBD, Lewy body disease; MCI, Mild cognitive impairment; nfv, nonfluent variant; PART, Primary age‐related tauopathy; PMI, post mortem interval, PPA, Primary progressive aphasia; VBI, Vascular brain injury.

^*Disease considered most likely to explain the clinical syndrome.

^**No control subject had limbic TDP‐43 proteinopathy.