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. 2020 Oct 13;12(19):19352–19364. doi: 10.18632/aging.103805

Figure 6.

Figure 6

CircPDZD8 upregulated the expression of CHD9 by modulating miR-197-5p in gastric cancer cells. (A–C) The mRNA and protein expression levels of CHD9 in SGC-7901 and MGC-803 cells transfected with si-NC, si-circPDZD8-1, si-circPDZD8-1 + inhibitor-NC or si-circPDZD8-1 + miR-197-5p-inhibitor were measured by RT-qPCR and western blot (MGC-803), respectively. (D) The proliferation of SGC-7901 and MGC-803 cells transfected with si-NC, si-circPDZD8-1, si-circPDZD8-1 + pcDNA3.1 or si-circPDZD8-1 + pcDNA3.1-CHD9 was examined by MTT assay. (E) The migration of SGC-7901 and MGC-803 cells transfected with si-NC, si-circPDZD8-1, si-circPDZD8-1 + pcDNA3.1 or si-circPDZD8-1 + pcDNA3.1-CHD9 was assessed by Transwell assay without Matrigel; *** P < 0.001.