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. 2020 Oct 7;12(19):19325–19334. doi: 10.18632/aging.103789

Table 6. Prognostic factors in cox regression for breast cancer.

Factors Univariate analysis Multivariate analysis
HR (95%CI) P HR (95%CI) P
Age,year
≥60 vs <60 1.43(0.64-3.19) 0.386 1.24(0.54-2.83) 0.617
Smoking
Yes vs No 0.85(0.29-2.49) 0.770 0.76(0.26-2.24) 0.613
Drinking
Yes vs No 0.36(0.11-1.19) 0.094 0.55(0.15-2.00) 0.365
BMI
>24 vs ≤24 1.06(0.48-2.36) 0.890 0.87(0.38-2.00) 0.747
Tumor size
≥2cm vs <2cm 0.82(0.37-1.81) 0.617 0.46(0.20-1.09) 0.077
Lymph node metastases
Yes vs No 2.35(1.05-5.28) 0.038 2.85(1.03-7.83) 0.043
Stage
III/IV vs I/II 3.81(1.52-9.51) 0.004 1.91(1.67-4.76) 0.016
ER
Positive vs negative 0.76(0.33-1.77) 0.524 0.61(0.24-1.58) 0.306
PR
Positive vs negative 1.40(0.64-3.09) 0.403 0.62(0.26-1.47) 0.273
Her-2
Positive vs negative 3.79(1.14-12.63) 0.030 2.37(1.73-7.56) 0.041
Treatment
Radiation vs chemoradiotherapy 2.27(1.05-4.92) 0.037 1.86(0.81-4.29) 0.146
rs4789936
CT vs CC 5.97(1.99-17.95) 0.001 4.65(1.26-17.18) 0.021
TT vs CC 5.28(1.39-20.03) 0.014 6.62(1.51-29.11) 0.012