Table 2. Univariate and multivariate analyses of overall survival in PC patients.

Parameters	Univariate analysis			Multivariate analysis
	HR	95%CI	P value	HR	95%CI	P value
Age	0.789	0.235-2.313	0.472	—	—	—
(≥65 vs <65)
Sex	1.382	0.516-3.636	0.673	—	—	—
(Female vs Male)
Distant metastasis	0.936	0.428-3.528	0.731	—	—	—
(No vs Yes)
Lymph node status	1.647	0.741-4.273	0.526	—	—	—
(No vs Yes)
Histologic grade	0.786	0.412-2.522	0.429	—	—	—
(High vs Low to medium)
Tumor size	1.637	1.145-4.176	0.002	1.412	1.031-3.629	0.017
(<5 vs ≥6)
TNM stage	3.176	1.776-4.361	0.024	2.134	1.412-4.062	0.033
(T1-T2 vs T3-T4)
Differentiation	1.462	1.162-2.863	0.007	1.235	0.814-2.431	0.037
(Well vs Moderate/Poor)
USP18 expression	2.874	1.451-4.524	0.001	1.662	1.214-3.647	0.007
(High vs Low)