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. 2020 Nov 23;11:574936. doi: 10.3389/fgene.2020.574936

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Copyright © 2020 Misra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Growth in research publications at PubMed pertaining to “exposomics” and “exposomics and aging” research. (B) Human aging from child birth (neonatal) through adolescence and the ultimate of life, death are riddled with exposure to chemicals surrounding us. As with the incremental aging one experiences physiological decline, possibly the cumulative exposome increases inside human body. (C) Human chemical exposure ranges from addiction (alcohol, drugs, cocaine, and smoking), to air pollution (PM, gases, industrial vapors), water (pollutions, pesticides, and PFAS), drugs (pharmaceuticals, and medications), the resident internal and external gut microbiome, domestic waste and indoor pollution (dust, cooking, and gases), occupational exposures (hospital disinfectants to asbestosis), pollution (fossil fuel burning to plastic), pets (carrying environmental pollution to microbiome), personal hygiene products (PHPs) (perfumes to soaps) to diet (and nutrition).