Table 3.
Clinical characteristics associated with WPAI:SpA scores in AS patients at baseline.
| Activity impairment | Absenteeism | Presenteeism | work productivity loss | |||||
|---|---|---|---|---|---|---|---|---|
| Univariable β (95% CI) | Multivariable β (95% CI) | Univariable β (95% CI) | Multivariable β (95% CI) | Univariable β (95% CI) | Multivariable β (95% CI) | Univariable β (95% CI) | Multivariable β (95% CI) | |
| Age | −0.11 (−0.82, 0.59) | NA | −0.48 (−1.1, 0.15) | NA | −0.69 (−1.40, 0.01) | −0.27 (−1.07, 0.53) | −0.69 (−1.40, 0.01) | −0.58 (−1.54, 0.37) |
| Marriage | −2.65 (−12.67, 7.36) | NA | −6.26 (−15.14, 2.61) | NA | −3.73 (−13.98, 6.51) | NA | −3.74 (−13.98, 6.51) | NA |
| Education | −0.41 (−7.2, 6.37) | NA | 3.5 (−2.6, 9.61) | NA | −0.88 (−7.83, 6.07) | NA | −0.88 (−7.83, 6.07) | NA |
| Disease duration | −0.002 (−0.71, 0.70) | NA | −0.71 (−1.35, −0.07) | −0.72 (−1.37, −0.08) | −0.77 (−1.49, −0.04) | −0.92 (−1.77, −0.06) | −0.77 (−1.49, −0.04) | −0.90 (−1.93, 0.12) |
| BASDAI | 8.98 (4.19, 13.78) | 2.08 (−4.12, 8.28) | 3.56 (−1.04, 8.17) | NA | 5.68 (0.47, 10.88) | −2.90 (−9.29, 3.48) | 5.68 (0.47, 10.88) | −1.18 (−8.70, 6.33) |
| BASFI | 7.68 (5.49, 9.87) | 4.94 (1.69, 8.19) | 1.49 (−1.06, 4.06) | NA | 6.28 (3.76, 8.79) | 4.63 (1.28, 7.98) | 6.28 (3.76, 8.79) | 5.35 (1.48, 9.22) |
| BASMI | 3.30 (1.31, 5.28) | −0.52 (−2.72, 1.68) | −0.29 (−2.22, 1.64) | NA | 1.22 (−0.95, 3.39) | NA | 1.21 (−0.95, 3.38) | NA |
| ASDAS | 13.45 (7.49, 19.41) | 0.25 (−9.52, 10.01) | 1.28 (−4.81, 7.36) | NA | 8.94 (2.33, 15.54) | 1.70 (−6.67, 10.08) | 8.94 (2.33, 15.55) | −3.09 (−13.29, 7.10) |
| ASQOL | 3.05 (1.87, 4.24) | 1.76 (0.52, 3.02) | 1.02 (−0.19, 2.23) | 0.94 (−0.40, 2.28) | 2.83 (1.57, 4.09) | 1.99 (0.65, 3.35) | 2.83 (1.57, 4.09) | 2.33 (0.80, 3.86) |
| EQ-5D | −37.21 (−60.95, −13.48) | −2.25 (−29.98, 25.48) | −19.55 (−41.49, 2.39) | −8.82 (−32.87, 15.21) | −37.46 (−61.84, −13.08) | −5.92 (−36.12, 24.27) | −37.46 (−61.84, −13.08) | −4.62 (−39.27, 30.02) |
| CRP | 0.34 (0.05, 0.62) | 0.26 (−0.13, 0.66) | −0.002 (−0.27, 0.27) | NA | 0.21 (−0.09, 0.51) | NA | 0.21 (−0.09, 0.51) | NA |
| ESR | 0.2 (−0.03, 0.44) | −0.07 (−0.31, 0.18) | 0.12 (−0.09, 0.34) | NA | 0.22 (−0.02, 0.46) | 0.007 (−0.24, 0.26) | 0.22 (−0.02, 0.46) | 0.14 (−0.16, 0.43) |
CI, Confidence Interval; NA, Not Available (only variables with P < 0.1 in the univariable linear regressions were included in the subsequent multivariable regression analyses); WPAI:SpA, Work productivity and activity impairment questionnaire in AS; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; ASDAS, Ankylosing Spondylitis Disease Activity Score; ASQoL, Ankylosing Spondylitis Quality of Life; EQ-5D, EuroQol-5 Dimensions; CRP, C-Reactive Protein; ESR, Erythrocyte Sedimentation Rate. Bold values are significant difference.